Our Week 10 Start ‘Em & Sit ‘Em is an in-depth look at the weekly NFL matchups and how they will impact your lineup decisions for your fantasy football team. Our list of Week 10 quarterback starts and sits features regular fantasy starters, as well as lesser-known players, who are likely to exceed expectations based on a favorable matchup, or fail to meet expectations due to the strength of their opponent.

Week 10 Start ‘Em, Sit ‘Em: QB | RB | WR | TE

Start ‘Em

Drew Brees NO vs. DEN

It has been long established that Drew Brees is a different quarterback in the Superdome. His home-road career splits are extremely lopsided, although that didn’t prevent him from hanging big numbers on the hapless 49ers defense last week in San Francisco. Regardless, Brees will take on the stout Broncos defense this week in New Orleans and fantasy owners should have reason to remain optimistic. Coupled with Brees’ home success is the fact that the Denver defense proved to be mortal last week, as the Raiders offense moved the ball at will. Don’t overthink it this week, Brees should remain in your lineup.

Carson Palmer ARI vs. SF

Coming off the bye, the Cardinals begin their pursuit back to relevancy in the NFC West and the playoff picture. First on-tap will be the NFC-worst 49ers who were absolutely annihilated by the Cardinals in Week 5. Carson Palmer should be able to string together one of his more productive games of the season this week, as I expect a demolition of the pathetic San Francisco defense. After David Johnson went bonkers in Week 5, the 49ers may be willing to take drastic measures to sell-out against the run (despite their consistent inability to do so). Either way, Palmer is a high-floor play for Week 10.

Ben Roethlisberger PIT vs. DAL

Similar to Brees, Ben Roethlisberger has historically posted huge numbers in his home venue. On the heels of a tough Week 9 loss to the division rival Ravens, Big Ben will be poised to get the Steelers offense rolling this week vs. the Dallas defense. I fully expect Roethlisberger to improve upon his sub-par performance from last week, as he continues to get healthier. Start ’em!

Sit ‘Em

Blake Bortles JAC vs. HOU

For the third week in a row, I’m putting Bortles in the sit ’em column. Over the previous two weeks, Bortles has been one of the absolute worst quarterbacks in the NFL, despite managing garbage time touchdowns in each of the last two starts. This week, he’ll get a Texans defense that boasts one of the better pass-defenses in the league. In last week’s loss against the Chiefs, it was more of the same for the third-year signal-caller. Bortles continuously overthrew his receivers and seemed like a guy completely rattled. Once again, he’s not an advisable play for Week 10.

Andy Dalton CIN @ NYG

Andy Dalton will lead the Bengals into the Meadowlands for a matchup with the Giants on Monday Night. New York has strung together back-to-back games where they have improved significantly on the defensive side of the ball. Landon Collins has been a catalyst in the secondary and the Giants defense will be key’ed on stopping A.J. Green, making Dalton cycle the ball to his other options in the passing game. I expect a balanced approach from Cincinnati, but don’t expect this to be a potent attack. Owners are better suited to find an alternative at quarterback for Week 10. Sit ’em!

Kirk Cousins MIN @ WAS

Coming off the bye, Kirk Cousins has a difficult task on hand for this week, as Washington hosts Minnesota on Sunday. While the Vikings have been struggling recently, their defense still remains an elite group and they should be hungry for what will be labeled as a must-win game for Minnesota. I expect this to be a relatively low-scoring game and think this will be a rare off-week for Cousins, who has been a quietly consistent option at the quarterback position for fantasy owners. Sit Captain Kirk this week vs. a stingy Vikings D.

For your final lineup decisions, check out our Week 10 player rankings and if you have any fantasy football questions, feel free to post them in our Fantasy Football Forum.